Modelling synergistic effects of appetite regulating hormones

Publication date: Available online 23 December 2015 Source:Synergy Author(s): Julie B. Schmidt, Christian Ritz We briefly reviewed one definition of dose addition, which is applicable within the framework of generalized linear models. We established how this definition of dose addition corresponds to effect addition in case only two doses per compound are considered for evaluating synergistic effects. The link between definitions was exemplified for an appetite study where two appetite hormones were studied. Graphical abstract Highlights
Source: Synergy - Category: Molecular Biology Source Type: research