Effects of a restricted fetal growth environment on human kidney morphology, cell apoptosis and gene expression

Conclusions:
Our study suggested increased apoptosis and decreased renin and angiotensinogen expression during human kidney development in an FGR environment. The current results will be helpful to further explore the molecular mechanism of FGR and facilitate future studies of hypertension and cardiovascular diseases and the establishment of preventive methods.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Wang, Y.-P., Chen, X., Zhang, Z.-K., Cui, H.-Y., Wang, P., Wang, Y. Tags: Original Articles Source Type: research