DNA damage and cellular abnormalities in tuberculosis, lung cancer and chronic obstructive pulmonary disease

Conclusion COPD patients showed cellular abnormalities that corresponded to cell death by apoptosis and necrosis, while patients with TB presented defects in cytokinesis and dysfunctions in DNA repair that resulted in the formation of micronucleus (MN) besides apoptotic and necrotic cells. Patients with COPD, TB and LC had a low frequency of permanent DNA damage.
Source: Multidisciplinary Respiratory Medicine - Category: Respiratory Medicine Source Type: research