Metabolism of xenobiotics by aldehyde oxidase.

Metabolism of xenobiotics by aldehyde oxidase.
Curr Protoc Toxicol. 2015;63:4.41.1-4.41.13
Authors: Dalvie D, Zientek M
Abstract
Aldehyde oxidase (AO) is a cytosolic molybdoflavoprotein whose contribution to the metabolism and clearance of xenobiotics-containing heterocyclic rings has attracted increased interest in recent years. This unit details methods for identification and confirmation of AO as a metabolic pathway as well as a method for estimating clearance of compounds that are AO substrates. © 2015 by John Wiley & Sons, Inc.
PMID: 25645247 [PubMed - in process]

Source: Current Protocols in Toxicology - December 21, 2015 Category: Toxicology Tags: Curr Protoc Toxicol Source Type: research