Double-blind randomized placebo-controlled multicenter clinical trial (phase IIa) on diindolylmethane’s efficacy and safety in the treatment of CIN: implications for cervical cancer prevention

Conclusions:
Thus, the use of diindolylmethane in the form of intravaginal suppositories can be effective in patients with CIN I–II and is not accompanied by clinically significant side effects. This approach could be a better option for young women with CIN I–II as it takes in attention their reproductive plans.Trial registrationID: ChiCTR-INR-15007497 (2 December 2015)

Source: Epidemiologic Perspectives and Innovations - December 21, 2015 Category: Epidemiology Authors: Levon AshrafianGennady SukhikhVsevolod KiselevMikhail PaltsevVadim DrukhIgor KuznetsovEkaterina MuyzhnekInna ApolikhinaEvgeniya Andrianova Source Type: research