Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy

Conclusions: Taken together, these data provide the evidence to show that genetic ablation of Ano5 in C57BL/6J mice does not cause overt pathology in skeletal and cardiac muscles, but Ano5 deficiency may lead to altered lipid metabolism and inflammation signaling.
Source: Epidemiologic Perspectives and Innovations - Category: Epidemiology Authors: Source Type: research