Genome wide expression after different doses of irradiation of a three-dimensional (3D) model of oral mucosal

Publication date: Available online 19 December 2015 Source:Genomics Data Author(s): Maria P. Lambros, Michael K. DeSalvo, Hari Chandana Mulamalla, Jonathan Moreno, Lavanya Kondapalli We evaluated a three-dimensional (3D) human oral cell culture that consisted of two types of cells, oral keratinocytes and fibroblasts as a model of oral mucositis which is a debilitating adverse effect of chemotherapy and radiation treatment. The 3D cell culture model was irradiated with 12 or 2Gy, and total RNA was collected 6h after irradiation to compare global gene expression profiles via microarray analysis. Here we provide detailed methods and analysis on these microarray data, which have been deposited in Gene Expression Omnibus (GEO): GSE62395.

Source: Genomics Data - December 20, 2015 Category: Genetics & Stem Cells Source Type: research