DNA damage and cellular abnormalities in tuberculosis, lung cancer and chronic obstructive pulmonary disease
Conclusion:
COPD patients showed cellular abnormalities that corresponded to cell death by apoptosis and necrosis, while patients with TB presented defects in cytokinesis and dysfunctions in DNA repair that resulted in the formation of micronucleus (MN) besides apoptotic and necrotic cells. Patients with COPD, TB and LC had a low frequency of permanent DNA damage.
Source: Epidemiologic Perspectives and Innovations - Category: Epidemiology Authors: Andréa da SilvaMaribel BrescianiThaís KarnoppAugusto WeberJoel EllwangerJoão HenriquesAndréia ValimLia Possuelo Source Type: research
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