Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures in multiple sclerosis
Conclusion:
We confirm that seizure frequency rises in MS. Type I GMLs in the temporal lobe underlie a loss of inhibitory interneurons in cortical layers IV and VI and these changes could together with concurrent infection enhance susceptibility to seizures.
Source: Multiple Sclerosis - Category: Neurology Authors: Nicholas, R., Magliozzi, R., Campbell, G., Mahad, D., Reynolds, R. Tags: Original Research Papers Source Type: research