Expression and immunolocalization of membrane progesterone receptors in the bovine oviduct

The oviduct plays a crucial role in the transport and maturation of gametes and ensures suitable conditions for fertility and early embryo development. One regulator of oviduct function is progesterone (P4), which affects the cell by interacting with nuclear progesterone receptors (PGR) as well as through non-genomic mechanisms, presumably involving membrane progesterone receptors. The aim of this study was to evaluate expression of mRNAs and proteins for progesterone receptor membrane component (PGRMC) 1 and 2 and membrane progestin receptors (mPR) α, β and γ and to use immunohistochemistry to demonstrate their cell-specific localization in the bovine oviduct.
Source: Domestic Animal Endocrinology - Category: Endocrinology Authors: Source Type: research