BMP signaling in vascular biology and dysfunction

The vascular system is critical for developmental growth as well as for tissue homeostasis and repair. It allows an adequate supply of oxygen and nutrients, removal of waste products, and transports liquid and cells through blood and lymphatic vessels. These vessels consist of endothelial cells (ECs) lining the interior surface, which – depending on the vessel type – are covered by pericytes or vascular smooth muscle cells (VSMCs). The vasculature is constantly adapting to meet demands from tissues, which undergo growth, repair or regression.
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Source Type: research