Dynamic Changes in White Matter Abnormalities Correlate With Late Improvement and Deterioration Following TBI: A Diffusion Tensor Imaging Study

Conclusions. These data can provide further insight into early and late pathophysiology, and begin to provide a framework that allows magnetic resonance imaging to be used as an imaging biomarker of therapy response. Knowledge of the temporal pattern of changes in TBI patient populations also provides a contextual framework for assessing imaging changes in individuals at any given time point.

Source: Neurorehabilitation and Neural Repair - December 14, 2015 Category: Neurology Authors: Newcombe, V. F. J., Correia, M. M., Ledig, C., Abate, M. G., Outtrim, J. G., Chatfield, D., Geeraerts, T., Manktelow, A. E., Garyfallidis, E., Pickard, J. D., Sahakian, B. J., Hutchinson, P. J. A., Rueckert, D., Coles, J. P., Williams, G. B., Menon, D. K. Tags: Clinical Research Articles Source Type: research