Well-differentiated endocrine cell carcinoma of ileum treated by laparoscopy-assisted surgery--a case report.

Well-differentiated endocrine cell carcinoma of ileum treated by laparoscopy-assisted surgery--a case report. Hiroshima J Med Sci. 2010 Jun;59(2):35-8 Authors: Sasada S, Ojima Y, Nishizaki M, Harano M, Matsukawa H, Aoki H, Shiozaki S, Ohno S, Ninomiya M, Matsuura H, Takakura N Abstract A 72-year-old woman presented at our hospital with a 1-year history of intermittent right lower abdominal pain. Colonoscopic examination revealed a submucosal tumor with a pitted surface in the terminal ileum. Histopathological diagnosis of the carcinoid tumor was made following biopsy. Blood serotonin and urine 5-hydroxy-indoleacetic acid levels were normal, and carcinoid syndrome was not detected. Enhanced abdominal computed tomography scan and 18F-fluorodeoxyglucose positron emission tomography failed to detect multiple lesions, lymph node swelling or distant metastasis. Laparoscopy-assisted ileocecal resection with lymph node dissection was performed. The resected specimen showed a submucosal tumor with a pitted surface 11 x 11 mm in size, located at the terminal ileum. Histopathological examination revealed a well-differentiated endocrine cell carcinoma with an invasion depth to the muscularis propria. Immunohistochemical analysis showed the tumor cells to be chromogranin A and CD56-positive. The patient had no sign of recurrence for 16 months. PMID: 20632686 [PubMed - indexed for MEDLINE]
Source: Hiroshima Journal of Medical Sciences - Category: Journals (General) Tags: Hiroshima J Med Sci Source Type: research