Association of high-density lipoprotein subclasses and incident coronary heart disease: The Jackson Heart and Framingham Offspring Cohort Studies

Conclusion
Smaller, denser HDL3-C levels are primarily responsible for the inverse association between HDL-C and incident CHD in this diverse group of primary prevention subjects. These findings have important implications ranging from considerations of HDL biology to interpretations of clinical trials utilizing HDL-C therapeutics.

Source: European Journal of Preventive Cardiology - December 11, 2015 Category: Cardiology Authors: Joshi, P. H., Toth, P. P., Lirette, S. T., Griswold, M. E., Massaro, J. M., Martin, S. S., Blaha, M. J., Kulkarni, K. R., Khokhar, A. A., Correa, A., D'Agustino, R. B., Jones, S. R., on behalf of the Lipoprotein Investigators Collaborative (LIC) Study Gro Tags: Original scientific papers Source Type: research