A Nuclear Magnetic Resonance Spectroscopy as a Method for Evaluation of In Vivo Poly-L-Lactide Biodegradation Kinetics From Stent-Polymer Matrices: An Experimental Study Utilizing Porcine Model of In-Stent Restenosis

Conclusions:
The utilization of NMR method for BP absorption kinetics evaluation is a useful tool, which may be widely adopted to test other biodegradable implants. Further, it may substantially improve their safety and efficacy by facilitating programmed polymer and drugs elution.

Source: Journal of Cardiovascular Pharmacology and Therapeutics - December 10, 2015 Category: Cardiology Authors: Orlik, B., Buszman, P. P., Krauze, A., Gasior, P., Desperak, P., Pajak, J., Kasperczyk, J., Janas, A., Jelonek, M., Handzlik-Orlik, G., Buszman, P. E., Milewski, K. Tags: Experimental Studies Source Type: research