Case series: agitation and hallucinations after exposure to 25B-NBOMe (“N-bomb”)

25B-NBOMe 3.5 out of 5 stars Case series: toxicity from 25B-NBOMe — a cluster of N-bomb cases. Gee P et al. Clin Toxicol 2015 Dec 1 [Epub ahead of print] Abstract The NBOMe series of drugs are substituted phenethylamines. They act as agonists at both the 5-HT2A serotonin receptors and the α-receptors. Because of these actions they can cause both hallucinations (5-HT2A effects) and the sympathomimetic toxidrome (α effects.) Since these drugs are so potent, they are often sold in the form of impregnated blotter paper and misrepresented as LSD. Street names include N-Bomb, Wizard, Smiles, and Blue Batman. “N-bomb” drugs include 25B-NBOMe,25I-NBOMe, and 25C-NBOMe. Documented exposure to 25B-NBOMe is relatively unusual — in fact, the authors state that only 5 cases have been reported previously. (There is at least one additional case — a fatality — that was published several months ago.) This observational case series describes 10 patients in New Zealand  with laboratory-confirmed exposure to 25B-NBOMe.  All patients were described as agitated and hallucinating, and were noted to have tachycardia and mydriasis. A majority were diaphoretic and had hypertension. The highest documented temperature in this series was 38oC (100.4oF.) Several patients exhibited bizarre behavior, including one who was “running into walls and repeatedly head-butting a concrete floor.” Most patients required high-dose benzodiazepines for behavioral control. One pa...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical @%B-NBOMe case series hallucinogenic stimulant n-bomb phenethylamine psychedlic Source Type: news