Adiponectin, leptin and insulin levels at birth and in early postnatal life in neonates with hypoxic ischemic encephalopathy.

CONCLUSIONS: Neonates who are suffering from HIE had lower serum levels of adiponectin and higher serum levels of leptin and insulin than normal healthy neonates at birth and during the early postnatal period. The decline of leptin and increased the insulin levels after birth in all neonates may be important for the stimulation of feeding behavior and the acquisition of energy homeostasis during the early postnatal life. Positive significant correlations between adiponectin, leptin, body weight and body mass indices were present in normal healthy neonates but not in neonates with HIE reflecting the effect of hypoxia on the regulatory mechanisms controlling the adipose tissue functions. PMID: 26629481 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26629481?dopt=Abstract

Source: Diabetes Metab - December 5, 2015 Category: Endocrinology Authors: El-Mazary AM, Nasif KA, Abdel-Hakeem GL, Sherif T, Farouk E, El-Gezawy EM Tags: J Diabetes Metab Disord Source Type: research