Synthesis of efficient gene delivery systems by grafting pegylated alkylcarboxylate chains to PAMAM dendrimers: Evaluation of transfection efficiency and cytotoxicity in cancerous and mesenchymal stem cells

This study proved the potential utility of alkylcarboxylate-grafted PAMAM dendrimers (G4 and G5) with or without PEG modification for efficient gene transfer into cancerous cells as well as MSCs.

Source: Journal of Biomaterials Applications - December 4, 2015 Category: Materials Science Authors: Ayatollahi, S., Hashemi, M., Kazemi Oskuee, R., Salmasi, Z., Mokhtarzadeh, A., Alibolandi, M., Abnous, K., Ramezani, M. Tags: Original Articles Source Type: research