Evaluating the association of IL-10 gene promoter-592 A/C Polymorphism with lupus nephritis susceptibility.

Conclusion IL-10 suggested to play a role in pathogenesis and development of LN.However,the promoter -592 A/C of IL-10 gene suggested to be not associated with serum IL-10 levels or LN susceptibility.Also it appears that promoter -592 A/C of IL-10 gene not associated with LN activity or the pathological classes of LN.
Source: Kidney Research and Clinical Practice - Category: Urology & Nephrology Source Type: research