Human miR-3145 inhibits influenza A viruses replication by targeting and silencing viral PB1 gene

In conclusion, this study demonstrated that human miR-3145 triggered silencing of viral PB1 genes and lead to inhibition of multiple subtypes of influenza viral replication. Therefore, hsa-miR-3145 might be useful for alternative treatment of influenza A viruses in the future.

Source: Experimental Biology and Medicine - December 2, 2015 Category: Research Authors: Khongnomnan, K., Makkoch, J., Poomipak, W., Poovorawan, Y., Payungporn, S. Tags: Biochemistry & amp;amp; Molecular Biology Source Type: research