Glomerular IgG subclasses in idiopathic and malignancy-associated membranous nephropathy

Conclusions
We have found that the absence of glomerular IgG4 and PLA2R is common in patients with malignancy-associated MN. In our material, IgG2 could not be used as a marker of underlying malignant disease. Finally, neither IgG1 nor IgG3 seems to be involved in the pathogenesis of MN.

Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Lonnbro-Widgren, J., Ebefors, K., Molne, J., Nystrom, J., Haraldsson, B. Tags: GLOMERULAR NEPHROPATHIES Source Type: research