Proximal tubular dysfunction and kidney injury associated with tenofovir in HIV patients: a case series

Conclusions Urinary phosphate wasting is a sensitive marker for TDF-induced proximal tubulopathy and is associated with unrecognized and permanent renal function decline. Tubular dysfunction can develop after years of TDF therapy in those with normal kidney function at the time of drug initiation. This suggests that continuing vigilance be maintained in all those on TDF.
Source: CKJ: Clinical Kidney Journal - Category: Urology & Nephrology Authors: Tags: ACUTE KIDNEY INJURY Source Type: research