Acute kidney injury associated with androgenic steroids and nutritional supplements in bodybuilders

Four bodybuilders who injected anabolic steroids and ingested commercial protein (78–104 g/day) and creatine (15 g/day) products presented with serum creatinine levels between 229.84 and 335.92 µmol/L (2.6–3.8 mg/dL). Renal biopsies revealed acute tubular necrosis. Four weeks after discontinuing injections and supplements, serum creatinine was in the normal range and estimated glomerular filtration rate > 1.00 mL/s (60 mL/min), including two patients with biopsies showing >30% interstitial fibrosis and tubular atrophy. The findings highlight a risk for acute and potentially chronic kidney injury among young men abusing anabolic steroids and using excessive amounts of nutritional supplements.

Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Almukhtar, S. E., Abbas, A. A., Muhealdeen, D. N., Hughson, M. D. Tags: ACUTE KIDNEY INJURY Source Type: research