Cholinergic anti-inflammatory pathway activity in dialysis patients: a role for neuroimmunomodulation?

Conclusions
The response of immune cells after LPS exposure and cholinergic stimulation suggests a functional CAP in dialysis patients. It may thus be possible to target the α7nAChR control of cytokine release as an anti-inflammatory strategy and thereby improve outcome in these patients.

Source: CKJ: Clinical Kidney Journal - September 24, 2015 Category: Urology & Nephrology Authors: Hilderman, M., Qureshi, A. R., Al-Abed, Y., Abtahi, F., Lindecrantz, K., Anderstam, B., Bruchfeld, A. Tags: HAEMODIALYSIS Source Type: research