Etiological diagnosis of granulomatous tubulointerstitial nephritis in the tropics

Conclusion
Etiological diagnosis of GIN is essential for timely and appropriate therapy. Tuberculosis is the commonest etiology (53%) in the tropics. Necrosis in granuloma, demonstration of acid fast bacilli, blood interferon gamma release assay and urine culture is not sensitive for the diagnosis of tuberculosis in GIN. Our findings suggest that tissue PCR for tuberculosis performed in an appropriate clinical setting is useful in the diagnostic evaluation of GIN.

Source: CKJ: Clinical Kidney Journal - September 24, 2015 Category: Urology & Nephrology Authors: Agrawal, V., Kaul, A., Prasad, N., Sharma, K., Agarwal, V. Tags: GRANULOMATOUS INTERSTITIAL NEPHRITIS Source Type: research