Granulomatous interstitial nephritis

We describe a patient with a history of multiple spinal surgeries complicated by wound infection who presented with confusion and rash with subsequent development of acute kidney injury. Urinalysis demonstrated pyuria and eosinophiluria, and renal biopsy revealed acute interstitial nephritis with granulomas. These findings were attributed to doxycycline treatment of his wound infection. This review explores the clinical associations, presentation, diagnosis, and treatment of this uncommon cause of acute kidney injury.
Source: CKJ: Clinical Kidney Journal - Category: Urology & Nephrology Authors: Tags: GRANULOMATOUS INTERSTITIAL NEPHRITIS Source Type: research