Pain pharmacology: focus on opioids.

Pain pharmacology: focus on opioids. Clin Cases Miner Bone Metab. 2014 Sep;11(3):165-8 Authors: Fornasari D Abstract The incidence of chronic pain is estimated to be 20-25% worldwide. Although major improvements in pain control have been obtained, more than 50% of the patients reports inadequate relief. It is accepted that chronic pain, if not adequately and rapidly treated, can become a disease in itself, often intractable and maybe irreversible. This is mainly due to neuroplasticity of pain pathways. In the present review I will discuss about pain depicting the rational for the principal pharmacological interventions and finally focusing on opioids, that represent a primary class of drug to treat pain. PMID: 25568646 [PubMed]
Source: Clinical Cases in Mineral and Bone Metabolism - Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research