Stimulation of regressing subordinate follicles of wave 2 with a gonadotropin product in heifers

The recovery of regressing wave-2 subordinate follicles was studied by treating heifers with a gonadotropin product that had about 84% and 16% of FSH and LH activity, respectively. A treated group (n = 8) received a single dose of 50 mg (2.5 mL) of the gonadotropin product, and a control group (n = 8) received 2.5 mL of saline vehicle. The group assignment of heifers was not known to the ultrasonographer who tracked the follicles and measured follicle diameters. Follicle measurements began on the day of expected follicle deviation in wave 2 (largest follicle closest to 8.5 mm) and treatment (hour 0) was given on Day 13.4 ± 0.2 (Day 0 = ovulation) when the dominant follicles of waves 1 and 2 were 14.1 ± 0.3 mm and 10.7 ± 0.1 mm, respectively.

Source: Domestic Animal Endocrinology - November 30, 2015 Category: Endocrinology Authors: O.J. Ginther, M.A.R. Siddiqui, J.M. Baldrighi, M.M. Hoffman Source Type: research