Insomnia Caused by Serotonin Depletion is Due to Hypothermia

Conclusions:These results indicate that early experiments using para-chlorophenylalanine that led to the conclusion that 5-hydroxytryptamine (5-HT) causes sleep were likely confounded by hypothermia. Temperature controls should be considered in experiments using 5-HT depletion.Citation:Murray NM, Buchanan GF, Richerson GB. Insomnia caused by serotonin depletion is due to hypothermia. SLEEP 2015;38(12):1985–1993.

http://www.journalsleep.org/ViewAbstract.aspx?pid=30343

Source: Sleep - December 1, 2015 Category: Sleep Medicine Source Type: research