Allergies and Disease Severity in Childhood Narcolepsy: Preliminary Findings

Conclusion:Involvement of the immune system plays an important role in the pathophysiology of narcolepsy. Current findings further suggest that an increased shift toward T helper 2 cells, as indicated by the presence of allergic conditions, may modulate the severity of the phenotype in childhood narcolepsy, and reduce the prevalence of cataplexy in these patients.Citation:Aydinoz S, Huang YS, Gozal D, Inocente CO, Franco P, Kheirandish-Gozal L. Allergies and disease severity in childhood narcolepsy: preliminary findings. SLEEP 2015;38(12):1981–1984.
Source: Sleep - Category: Sleep Medicine Source Type: research