Interictal Hippocampal Spiking Influences the Occurrence of Hippocampal Sleep Spindles

Conclusions:Hippocampal spindles represent a physiological phenomenon, with an expression that is diminished in epilepsy affecting the temporal lobe. Hippocampal spiking lowered the rate of hippocampal spindles, suggesting that epileptic discharges may at least in part be a transformation of these physiological events, similar to the hypothesis considering generalized spike-and-waves a transformation of frontal spindles.Citation:Frauscher B, Bernasconi N, Caldairou B, von Ellenrieder N, Bernasconi A, Gotman J, Debeau F. Interictal hippocampal spiking influences the occurrence of hippocampal sleep spindles. SLEEP 2015;38(12):1927–1933.
Source: Sleep - Category: Sleep Medicine Source Type: research