Noninvasive Fractional Flow Reserve for the Diagnosis of Lesion-specific Ischemia: A Case Example

Jesper Møller Jensen, Lars Christian Gormsen, Henning Mølgaard, Bjarne Linde NørgaardJournal of Clinical Imaging Science 2015 5(1):3-3A physically active 52-year-old male with atypical chest pain was referred to our department. A coronary computed tomography angiography (CCTA) showed a stenotic plaque in the mid left anterior descending coronary artery (LAD). A rest-stress Rubidium-82 myocardial perfusion was normal. One year later the patient sustained a cardiac arrest and percutaneous coronary intervention of the mid-LAD was successfully performed. The original CCTA data were submitted for noninvasive determination of fractional flow reserve (FFR CT ) revealing an ischemia-producing lesion in the mid-LAD. This case demonstrates the inherent limitations of assessing lesion-specific ischemia. FFR CT shows promise as a new method for future selection of patients for coronary angiography.

Source: Journal of Clinical Imaging Science - January 30, 2015 Category: Radiology Authors: Jesper Møller JensenLars Christian GormsenHenning MølgaardBjarne Linde Nørgaard Source Type: research