A method for the measurement of pressure sensitivity of carotid-femoral pulse wave velocity in humans

Background: Carotid-femoral pulse wave velocity (cfPWV), a marker of cardiovascular disease, is modified by both blood pressure and changes in arterial wall properties. Current cfPWV measurement does not differentiate between effects of blood pressure and arterial wall properties. Animal studies show that the blood pressure sensitivity of arterial PWV is indicative of blood vessel remodeling. Measurement of this parameter in humans requires a forced change in blood pressure, as can be achieved by Valsalva maneuver.
Source: Artery Research - Category: Cardiology Authors: Source Type: research