Effect of aliskiren on vascular remodeling in small retinal circulation

Background: In hypertension changes in small arterial structure are characterized by an increased wall-to-lumen ratio (WLR). These adaptive processes are modulated by the renin angiotensin system. It is unclear whether direct renin inhibitors exert protective effects on small arteries in hypertensive patients.

Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Christian Ott, Agnes Jumar, Joanna Harazny, Stephanie Schmidt, Roland Schmieder Source Type: research