A novel marker expresses the effect of the nonlinearity in the arterial pressure-volume relationship on the pulse pressure: Characteristics and prognostic significance in hypertensive patients

Arterial pressure-volume relationship frequently deviates from the linearity expected from an ideal elastic tube. As a result, pulse pressure (PP) can be split into an ‘elastic’ component (elPP) and an excess value PP-elPP. We define the ratio (PP-elPP)/elPP as arterial nonlinearity marker (NLM). OBJECTIVE: Determining NLM from ambulatory BP (ABP) measurements and investigating its clinical and demographic characteristics and prognostic significance in hypertensive patients. METHODS: Following a previously described model-based procedure, NLM was determined from the variability of systolic BP (SBP) and diastolic BP (DBP).

Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Benjamin Gavish, Michael Bursztyn Source Type: research