Ischemia-related changes in circulating stem and progenitor cells and associated clinical characteristics in peripheral artery disease

In conclusion, treadmill exercise-induced lower-extremity ischemia is associated with acute increases in circulating SPCs among people with PAD. More severe PAD is associated with a higher prevalence of SPC increases in response to lower-extremity ischemia. Further prospective study is needed to establish the prognostic significance of ischemia-related increases in SPCs among patients with PAD.

Source: Vascular Medicine - November 23, 2015 Category: Internal Medicine Authors: Saber, R., Liu, K., Ferrucci, L., Criqui, M. H., Zhao, L., Tian, L., Guralnik, J. M., Liao, Y., Domanchuk, K., Kibbe, M. R., Green, D., Perlman, H., McDermott, M. M. Tags: Original Articles Source Type: research