Embroidered and surface coated polycaprolactone-co-lactide scaffolds: a potential graft for bone tissue engineering.

This article reviews a possible strategy using a tissue engineering approach and systematically describes a series of experiments evaluating the properties of an embroidered and surface coated polycaprolactone-co-lactide scaffold being considered as bone graft substitute for large bone defects. The scaffold design and fabrication, the scaffolds properties, as well as its surface modification and their influence in vitro are evaluated, followed by in vivo analysis of the scaffolds using orthotopic implantation models in small and large animals. PMID: 23507867 [PubMed - indexed for MEDLINE]
Source: Biomatter - Category: Biotechnology Tags: Biomatter Source Type: research