Characterization of the picrotoxin site of GABAA receptors.

Characterization of the picrotoxin site of GABAA receptors. Curr Protoc Pharmacol. 2013;63:Unit 1.18. Authors: Mehta AK, Ticku MK Abstract This unit describes an in vitro assay for characterization of the picrotoxin site of GABAA receptors in rat brain membranes using various radioligands. Methods and representative data for Scatchard analysis (Kd, Bmax determination), association kinetics, dissociation kinetics, and competition assays (IC50, Ki determination) are included. PMID: 24510752 [PubMed - indexed for MEDLINE]
Source: Current Protocols in Pharmacology - Category: Drugs & Pharmacology Tags: Curr Protoc Pharmacol Source Type: research