Intestinal pseudo-obstruction following oral baclofen: An unusual complication

We report a 50-year-old male with spasticity following cervical discectomy (C3-4) on oral baclofen for 6 months with intestinal pseudo-obstruction. He had undergone open suprapubic cystostomy for traumatic urethral injury, 45 days prior to the presentation and adhesive intestinal obstruction was also considered a possibility. However, there were no air fluid levels on abdominal radiographs and ultrasound abdomen was non-contributory. Withdrawal of baclofen was therapeutic in this patient. This case is being reported to highlight the rare possibility of oral baclofen induced intestinal pseudo-obstruction.

Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Vilvapathy Senguttuvan KarthikeyanKuppusamy SenthilkumaranBettaiyagowder EaswaranRajamariappan Rajbhaskar Source Type: research