The impact of the Val158Met COMT polymorphism on context processing in patients on the schizophrenia spectrum and their relatives

Conclusions Deficits in context processing in schizophrenic patients and their families are influenced by the Val158Met COMT functional polymorphism, likely as a consequence of reduced dopamine availability in the PFC.
Source: Schizophrenia Research: Cognition - Category: Psychiatry Source Type: research