3D Surface-based Registration of Ultrasound and Histology in Prostate Cancer Imaging

Prostate cancer (PCa) is the type of cancer with the highest incidence and second highest mortality among males in the United States [1]. Despite the statistics of this cancer type, the main diagnostic technique, systematic biopsy, has major drawbacks. Firstly, being invasive, it can cause infections and hematuria [2]. Secondly, tumors can be missed by the biopsy needle [3], resulting in poor sensitivity of this diagnostic tool. Thirdly, tumors can be undergraded when the more aggressive region of a tumor is missed [4], leading to undertreatment.

Source: Computerized Medical Imaging and Graphics - November 16, 2015 Category: Radiology Authors: Stefan G. Schalk, Arnoud Postema, Tamerlan A. Saidov, Libertario Demi, Martijn Smeenge, Jean J.M.C.H. de la Rosette, Hessel Wijkstra, Massimo Mischi Source Type: research