Neutrophil-gelatinase associated lipocalin (N-GAL) to assess perioperative acute kidney injury in hand-assisted laparoscopic donor nephrectomy: A pilot study

Conclusion Significant AKI occurs with live donor nephrectomy. This is difficult to quantify using standard biochemistry due to the overwhelming effect of nephrectomy on eGFR. AKI is associated with poorer donor eGFR at 6 weeks. Pre-operative hypovolaemia plays a role in AKI. Optimisation of perioperative fluid management is likely to have a protective role.
Source: Indian Journal of Transplantation - Category: Transplant Surgery Source Type: research