GDM Alters Expression of Placental Estrogen Receptor {alpha} in a Cell Type and Gender-Specific Manner

Conclusion: Gestational diabetes mellitus affects expression of placental ERα in a cell type-dependent way, on epigenetic level. These data link GDM with epigenetic deregulations of ERα expression and open new insights into the intrauterine programming hypothesis of GDM.

http://rsx.sagepub.com/cgi/content/abstract/22/12/1488?rss=1

Source: Reproductive Sciences - November 13, 2015 Category: Reproduction Medicine Authors: Knabl, J., Hiden, U., Hüttenbrenner, R., Riedel, C., Hutter, S., Kirn, V., Günthner-Biller, M., Desoye, G., Kainer, F., Jeschke, U. Tags: Original Articles Source Type: research