Effects of lead exposure on dendrite and spine development in hippocampal dentate gyrus areas of rats

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Lead exposure during pregnancy and lactation disturbed the dendrite extension, spine protrusion and maturity of granule cells in the hippocampal DG areas of rats. A decrease in Arc/Arg 3.1 expression may be involved in this effect.

Source: Synapse - November 12, 2015 Category: Neurology Authors: Fan Hu, Meng‐meng Ge, Wei‐heng Chen Tags: Research Article Source Type: research