Assessment of an ELISA for serodiagnosis of active pulmonary tuberculosis in a Cuban population

Conclusions An ELISA using a multi-antigen mix containing recombinant immuno-dominant antigens of Mycobacterium tuberculosis, namely, rCFP-10, rESAT-6, rAPA, rPstS-1 and rAg85, increases the sensitivity and specificity compared with that using the single antigens and shows potential as a complementary tool for the diagnosis of active pulmonary tuberculosis in Cuba.
Source: Asian Pacific Journal of Tropical Disease - Category: Tropical Medicine Source Type: research