Expression and Clinical Significance of MDM2 and p21WAF1 Proteins in Human Glioma

Objective: To explore the expressions and clinical significance of murine double-minute 2 (MDM2) and p21WAF1 proteins in human glioma. Methods: The expressions of MDM2 and p21WAF1 proteins were, respectively, detected with immunohistochemistry S-P method in glioma and normal brain tissue, and then the relations of their expressions with clinical and pathologic parameters were analyzed. Results: The expressions of MDM2 and p21WAF1 proteins were significantly higher in glioma than in normal brain tissue (P
Source: Neurosurgery Quarterly - Category: Neurosurgery Tags: Original Articles Source Type: research