Adenosine A2B receptor stimulates angiogenesis by inducing VEGF and eNOS in human microvascular endothelial cells

In conclusion, the A2B AR activation-driven angiogenesis via cAMP-PKA-CREB mediated VEGF production and PI3K/AKT-dependent upregulation of eNOS in HMEC-1.

Source: Experimental Biology and Medicine - October 30, 2015 Category: Research Authors: Du, X., Ou, X., Song, T., Zhang, W., Cong, F., Zhang, S., Xiong, Y. Tags: Cell & amp;amp; Developmental Biology Source Type: research