Defective secretion of PGF2α during development of idiopathic persistent corpus luteum in mares

Five mares that developed idiopathic persistent corpus luteum (PCL) were compared with 5 mares with apparently normal interovulatory intervals (IOI). Progesterone (P4) and a metabolite of PGF2α (PGFM) were assayed daily beginning on the day of ovulation (Day 0). Transition between the end of an initial progressive P4 increase and the beginning of a gradual decrease in P4 occurred on mean Day 6. The gradual decrease in P4 between Days 6 and 12 was less (approached significance, P < 0.06) in the PCL group than in the IOI group.

Source: Domestic Animal Endocrinology - October 28, 2015 Category: Endocrinology Authors: O.J. Ginther, T. Castro, J.M. Baldrighi, C.A. Wolf, V.G. Santos Source Type: research