Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

This study highlights the utility of using prior functional data for sequence variants in prioritization analyses to search for robust signals in the suggestive range.

Source: Carcinogenesis - October 29, 2015 Category: Cancer & Oncology Authors: Brenner, D. R., Amos, C. I., Brhane, Y., Timofeeva, M. N., Caporaso, N., Wang, Y., Christiani, D. C., Bickeböller, H., Yang, P., Albanes, D., Stevens, V. L., Gapstur, S., McKay, J., Boffetta, P., Zaridze, D., Szeszenia-Dabrowska, N., Lissowska, J. Tags: Original Manuscript Source Type: research