Characterization, quantum, antibacterial, antifungal, antioxidant and acute toxicity studies on Hg(II) and Cd(II) complexes of allyl and ethyl thiosemicarbazides derived from 2-aminothiazole-4-yl aceto hydrazide

Publication date: Available online 23 October 2015 Source:Egyptian Journal of Basic and Applied Sciences Author(s): T.A. Yousef, G.M. Abu El-Reash, H.I. El-Sayad, O.A. El-Gammal, B.M. Sharaa Two thiosemicarbazide ligands were derived from the addition of 2-(2-aminothiazol-4-ylaceto) hydrazid to both ethyl isothiocynate (H2TAET) and allyl isothiocynat (H2TAAT) where their Cd (II) and Hg (II) complexes were synthesized and characterized by traditional techniques. The complexes were assigned the formulas, [Cd(HTAET)(H2O)Cl](H2O)2, [Hg(TAET)(H2O)2]2, [Cd(HTAAT)(H2O)Cl]H2O and [Hg(H2TAAT)(H2O)Cl2], respectively. In Cd (II) complexes, the IR spectra show that the ligands behave as monobasic bidentate through (C = N) thiazol ring and deprotonated enolized (CO). In Hg (II) complexes, H2TAET acts as dibasic tridentate (NSO) via thiol (CS), enolized (CO) and new azomethine, (N = C)* groups, while H2TAAT act as neutral tridentate (NNO) through (C = N) of thiazol ring, (CO) and new (C = N) due to (SH) formation. A tetrahedral for Cd (II) complexes, square pyramidal for [Hg(TAET)(H2O)2]2 and octahedral for [Hg(H2TAAT)(H2O)Cl2] geometries were proposed. The data of theoretical and experimental vibrational frequencies of ligands are comparable. The data calculated of HOMO– LUMO energies gap decided the possibility of charge transfer within the molecule. The binding energies calculations showed the higher stability of complexes than that of ligands. The kineti...
Source: Egyptian Journal of Basic and Applied Sciences - Category: Science Source Type: research